Description
Cephalosporins (sef-a-loe-SPOR-ins)
are used in the treatment of infections
caused by bacteria. They work by killing bacteria or preventing their growth.
Cephalosporins are used to treat infections in many different parts of
the body. They are sometimes given with other antibiotics. Some cephalosporins
given by injection are also used to prevent infections before, during, and
after surgery. However, cephalosporins will not work for colds, flu, or other
virus infections.
Cephalosporins are available only with your doctor's prescription, in the
following dosage forms:
Oral
-
Cefaclor
-
Capsules (U.S. and Canada)
-
Oral suspension (U.S. and Canada)
-
Extended-release tablets (U.S.)
-
Cefadroxil
-
Capsules (U.S. and Canada)
-
Oral suspension (U.S.)
-
Tablets (U.S.)
-
Cefdinir
-
Capsules (U.S.)
-
Oral Suspension (U.S.)
-
Cefixime
-
Oral suspension (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Cefpodoxime
-
Oral suspension (U.S.)
-
Tablets (U.S.)
-
Cefprozil
-
Oral suspension (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Ceftibuten
-
Capsules (U.S.)
-
Oral suspension (U.S.)
-
Cefuroxime
-
Oral suspension (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Cephalexin
-
Capsules (U.S. and Canada)
-
Oral suspension (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Cephradine
-
Capsules (U.S.)
-
Oral suspension (U.S.)
Parenteral
-
Cefamandole
-
Injection (U.S. and Canada)
-
Cefazolin
-
Injection (U.S. and Canada)
-
Cefepime
-
Injection (U.S. and Canada)
-
Cefonicid
-
Cefoperazone
-
Cefotaxime
-
Injection (U.S. and Canada)
-
Cefotetan
-
Injection (U.S. and Canada)
-
Cefoxitin
-
Injection (U.S. and Canada)
-
Ceftazidime
-
Injection (U.S. and Canada)
-
Ceftizoxime
-
Injection (U.S. and Canada)
-
Ceftriaxone
-
Injection (U.S. and Canada)
-
Cefuroxime
-
Injection (U.S. and Canada)
-
Cephalothin
-
Cephapirin
Before Using This Medicine
In deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For the cephalosporins,
the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or
allergic reaction to any of the cephalosporins, penicillins, penicillin-like
medicines, or penicillamine. Also tell your health care professional if you
are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy--Studies have not been done in humans. However, most
cephalosporins have not been reported to cause birth defects or other problems
in animal studies. Studies in rabbits have shown that cefoxitin may increase
the risk of miscarriages and cause other problems.
Breast-feeding--Most cephalosporins pass into breast milk, usually
in small amounts. However, cephalosporins have not been reported to cause
problems in nursing babies.
Children--Many cephalosporins have been tested in children
and, in effective doses, have not been shown to cause different side effects
or problems than they do in adults. However, there are some cephalosporins
that have not been tested in children up to 1 year of age.
Older adults--Cephalosporins have been used in the elderly, and
they are not expected to cause different side effects or problems in older
people than they do in younger adults.
Other medicines--Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
a cephalosporin, it is especially important that your health care professional
know if you are taking any of the following:
-
Alcohol or alcohol-containing medicine (cefamandole, cefoperazone,
and cefotetan only)--Using alcohol and these cephalosporins together
may cause abdominal or stomach cramps, nausea, vomiting, headache, dizziness
or light-headedness, shortness of breath, sweating, or facial flushing; this
reaction usually begins within 15 to 30 minutes after alcohol is consumed
and usually goes away over several hours
-
Anticoagulants (blood thinners) or
-
Carbenicillin by injection (e.g., Geopen) or
-
Dipyridamole (e.g., Persantine) or
-
Divalproex (e.g., Depakote) or
-
Heparin (e.g., Hepalean, Liquaemin) or
-
Pentoxifylline (e.g., Trental) or
-
Plicamycin (e.g., Mithracin) or
-
Sulfinpyrazone (e.g., Anturane) or
-
Ticarcillin (e.g., Ticar) or
-
Thrombolytic agents or
-
Valproic acid (e.g., Depakene)--Any of these medicines may increase
the chance of bleeding, especially when used with cefamandole, cefoperazone,
or cefotetan
-
Iron --Iron supplements, including multivitamins that contain
iron, may decrease the effect of cefdinir. However, iron-fortified infant
formula does not decrease the effect cefdinir
-
Probenecid (e.g., Benemid) (except cefoperazone, ceftazidime, or
ceftriaxone)--Probenecid increases the blood level of many cephalosporins.
Although probenecid may be given with a cephalosporin by your doctor purposely
to increase the blood level to treat some infections, in other cases this
effect may be unwanted and may increase the chance of side effects
Other medical problems--The presence of other medical
problems may affect the use of cephalosporins. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Bleeding problems, history of (cefamandole, cefoperazone, and cefotetan
only)--These medicines may increase the chance of bleeding
-
Kidney disease--Some cephalosporins need to be given at a lower
dose to people with kidney disease. Also, cephalothin, especially, may increase
the chance of kidney damage
-
Liver disease (cefoperazone only)--Cefoperazone needs to be
given at a lower dose to people with liver and kidney disease
-
Phenylketonuria--Cefprozil oral suspension contains phenylalanine
-
Stomach or intestinal disease, history of (especially colitis, including
colitis caused by antibiotics, or enteritis)--Cephalosporins may cause
colitis in some patients
Proper Use of This Medicine
Cephalosporins
may be taken on a full or empty stomach. If this medicine upsets your stomach,
it may help to take it with food.
Cefaclor extended-release tablets, cefpodoxime, and cefuroxime axetil should
be taken with food to increase absorption of the medicine. Ceftibuten oral
suspension should be taken on an empty stomach, at least 2 hours before or
1 hour after a meal.
For patients taking the oral liquid
form of
this medicine:
-
This medicine is to be taken by mouth. Use a specially marked measuring
spoon or other device to measure each dose accurately. The average household
teaspoon may not hold the right amount of liquid.
-
Do not use after the expiration date on the label since the medicine
may not work properly after that date. Check with your pharmacist if you have
any questions about this.
To help clear up your infection completely, keep taking
this medicine for the full time of treatment
, even if you begin to
feel better after a few days. If you have a ``strep''
infection, you should keep taking this medicine for at least 10 days. This
is especially important in ``strep'' infections since serious heart or kidney
problems could develop later
if your infection is not cleared up completely.
Also, if you stop taking this medicine too soon, your symptoms may return.
This medicine works best when there is a constant amount in the blood or
urine. To help keep the amount constant, do not miss
any doses. Also, it is best to take the doses at evenly spaced times, day
and night
. For example, if you are to take four doses a day, the doses
should be spaced about 6 hours apart. If this interferes with your sleep or
other daily activities, or if you need help in planning the best times to
take your medicine, check with your health care professional.
Dosing--The dose of these medicines will be different
for different patients. Follow your doctor's orders or
the directions on the label
. The following information includes only
the average doses of these medicines. Your dose may be different if you have
kidney disease. If your dose is different, do not change
it
unless your doctor tells you to do so.
The number of capsules or tablets or teaspoonfuls of suspension that you
take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and
the length of time you take the medicine depend on the medical problem for
which you are taking a cephalosporin
.
For cefaclor
-
For bacterial infections:
-
For capsule
or oral suspension
dosage form:
-
Adults and teenagers--250 to 500 milligrams (mg) every eight
hours.
-
Infants and children 1 month of age and older--6.7 to 13.4 mg
per kilogram (kg) (3.04 to 6.09 mg per pound) of body weight every eight hours,
or 10 to 20 mg per kg (4.54 to 9.09 mg per pound) of body weight every twelve
hours.
-
For extended-release tablet
dosage form:
-
Adults and teenagers 16 years of age and older--375 to 500 mg
every twelve hours for seven to ten days.
-
Children up to 16 years of age--Use and dose must be determined
by your doctor.
For cefadroxil
-
For bacterial infections:
-
For oral
dosage forms (capsules, oral
suspension, or tablets):
-
Adults and teenagers--500 milligrams (mg) or 1 gram every twelve
hours, or 1 or 2 grams once a day.
-
Children--15 mg per kilogram (kg) (6.81 mg per pound) of body
weight every twelve hours, or 30 mg per kg (13.63 mg per pound) of body weight
once a day.
For cefamandole
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams (mg) to 2 grams every four
to eight hours, injected into a muscle or vein.
-
Infants and children 1 month of age and older--8.3 to 50 mg
per kilogram (kg) (3.77 to 22.72 mg per pound) of body weight every four to
eight hours, injected into a muscle or vein.
For cefazolin
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--250 milligrams (mg) to 1.5 grams every
six to twelve hours, injected into a muscle or vein.
-
Infants and children 1 month of age and older--6.25 to 25 mg
per kilogram (kg) (2.84 to 11.36 mg per pound) of body weight every six hours,
or 8.3 to 33.3 mg per kg (3.77 to 15.13 mg per pound) of body weight every
eight hours, injected into a muscle or vein.
-
Newborns--20 mg per kg (9.09 mg per pound) of body weight every
eight to twelve hours, injected into a vein.
For cefdinir
-
For bacterial infections:
-
For capsule or oral suspension
dosage form:
-
Adults and teenagers--300 milligrams (mg) ever twelve hours
or 600 mg once a day for 5 to 10 days.
-
Infants and children 6 months of age and older--7 milligrams
(mg) per kilogram (3.18 mg per pound) of body weight every twelve hours or
14 mg per kilogram (6.36 mg per pound) once a day for 5 to 10 days.
For cefepime
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams to 2 grams every eight
to twelve hours, injected into a muscle or vein, for seven to ten days.
-
Infants and children 2 months to 16 years of age--50 milligrams
per kilogram body weight injected into muscle or vein, every eight to twelve
hours, for seven to ten days.
For cefixime
-
For bacterial infections:
-
For oral
dosage forms (oral suspension
or tablets):
-
Adults and teenagers--200 milligrams (mg) every twelve hours,
or 400 mg once a day. Gonorrhea is treated with a single, oral dose of 400
mg.
-
Children 6 months to 12 years of age--4 mg per kilogram (kg)
(1.81 mg per pound) of body weight every twelve hours, or 8 mg per kg (3.63
mg per pound) of body weight once a day.
-
Infants up to 6 months of age--Use and dose must be determined
by your doctor.
For cefonicid
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams (mg) to 2 grams every twenty-four
hours, injected into a muscle or vein.
-
Children--Use and dose must be determined by your doctor.
For cefoperazone
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--1 to 6 grams every twelve hours, or 2
to 4 grams every eight hours, injected into a muscle or vein.
-
Children--Use and dose must be determined by your doctor.
For cefotaxime
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--1 to 2 grams every four to twelve hours,
injected into a muscle or vein. Gonorrhea is usually treated with a single
dose of 500 milligrams (mg) or 1 gram, injected into a muscle.
-
Children over 50 kg of body weight (110 pounds)--1 to 2 grams
every four to twelve hours, injected into a muscle or vein.
-
Infants and children 1 month of age and older and up to 50 kg of
body weight (110 pounds)--8.3 to 30 mg per kg (3.77 to 13.63 mg per pound)
of body weight every four hours, or 12.5 to 45 mg per kg (5.68 to 20.45 mg
per pound) of body weight every six hours, injected into a muscle or vein.
-
Newborns 1 to 4 weeks of age--50 mg per kg (22.72 mg per pound)
of body weight every eight hours, injected into a vein.
-
Newborns up to 1 week of age--50 mg per kilogram (kg) (22.72
mg per pound) of body weight every twelve hours, injected into a vein.
For cefotetan
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams to 3 grams every twelve
hours, or 1 or 2 grams every twenty-four hours, injected into a muscle or
vein.
-
Children--Use and dose must be determined by your doctor.
For cefoxitin
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--1 to 3 grams every four to eight hours,
injected into a vein.
-
Infants and children 3 months of age and older--13.3 to 26.7
milligrams (mg) per kilogram (kg) (6.04 to 12.13 mg per pound) of body weight
every four hours, or 20 to 40 mg per kg (9.09 to 18.18 mg per pound) of body
weight every six hours, injected into a vein.
-
Infants 1 to 3 months of age--20 to 40 mg per kg (9.09 to 18.18
mg per pound) of body weight every six to eight hours, injected into a vein.
-
Newborns 1 to 4 weeks of age--20 to 40 mg per kg (9.09 to 18.18
mg per pound) of body weight every eight hours, injected into a vein.
-
Premature infants weighing 1500 grams and over to newborns up to
1 week of age--20 to 40 mg per kg (9.09 to 18.18 mg per pound) of body
weight every twelve hours, injected into a vein.
For cefpodoxime
-
For bacterial infections:
-
For oral
dosage forms (oral suspension
or tablets):
-
Adults and teenagers--100 to 400 milligrams (mg) every twelve
hours for five to fourteen days. Gonorrhea is treated with a single, oral
dose of 200 mg.
-
Infants and children 5 months to 12 years of age--5 mg per kilogram
(kg) (2.27 mg per pound) of body weight every twelve hours for five to ten
days, or 10 mg per kg (4.54 mg per pound) of body weight every twenty-four
hours for ten days.
-
Infants up to 5 months of age--Use and dose must be determined
by your doctor.
For cefprozil
-
For bacterial infections:
-
For oral
dosage forms (oral suspension
or tablets):
-
Adults and teenagers--250 or 500 milligrams (mg) every twelve
to twenty-four hours for ten days.
-
Children 2 to 12 years of age--7.5 to 20 mg per kilogram (kg)
(3.4 to 9.09 mg per pound) of body weight every twelve to twenty-four hours
for ten days.
-
Infants and children 6 months to 12 years of age--7.5 to 15
mg per kg (3.4 to 6.81 mg per pound) of body weight every twelve hours for
ten days.
-
Infants up to 6 months of age--Use and dose must be determined
by your doctor.
For ceftazidime
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--250 milligrams (mg) to 2 grams every eight
to twelve hours, injected into a muscle or vein. Patients with cystic fibrosis
may receive 30 to 50 mg per kilogram (kg) (13.63 to 22.72 mg per pound) of
body weight every eight hours, injected into a vein.
-
Infants and children 1 month to 12 years of age--30 to 50 mg
per kg (13.63 to 22.72 mg per pound) of body weight every eight hours, injected
into a vein.
-
Newborns up to 4 weeks of age--30 mg per kg (13.63 mg per pound)
of body weight every twelve hours, injected into a vein.
For ceftibuten
-
For bacterial infections:
-
For oral
dosage forms (capsules or oral
suspension):
-
Adults and teenagers--400 milligrams (mg) once a day for ten
days.
-
Infants and children 6 months to 12 years of age--9 mg per kilogram
(4.09 mg per pound) of body weight once a day for ten days.
-
Infants up to 6 months of age--Use and dose must be determined
by your doctor.
For ceftizoxime
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams (mg) to 4 grams every eight
to twelve hours, injected into a muscle or vein. Gonorrhea is treated with
a single dose of 1 gram, injected into a muscle.
-
Infants and children 6 months of age and older--50 mg per kilogram
(22.72 mg per pound) of body weight every six to eight hours, injected into
a muscle or vein.
-
Infants up to 6 months of age--Use and dose must be determined
by your doctor.
For ceftriaxone
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--1 to 2 grams every twenty-four hours,
or 500 milligrams (mg) to 1 gram every twelve hours, injected into a muscle
or vein. Gonorrhea is treated with a single 250-mg dose, injected into a muscle.
-
Infants and children--25 to 37.5 mg per kilogram (kg) (11.36
to 17.04 mg per pound) of body weight every twelve hours, or 50 to 75 mg per
kg (22.72 to 34.09 mg per pound) of body weight once a day, injected into
a muscle or vein. Meningitis is treated with an initial dose of 100 mg per
kg, then 100 mg per kg once a day or 50 mg per kg two times a day.
For cefuroxime
-
For bacterial infections:
-
For oral suspension
dosage form:
-
Adults and teenagers--The oral suspension is usually used only
for children. Refer to the dosing for cefuroxime tablets.
-
Infants and children 3 months to 12 years of age--10 to 15 milligrams
(mg) per kilogram (kg) (4.54 to 6.81 mg per pound) of body weight every twelve
hours for ten days.
-
For tablet
dosage form:
-
Adults and teenagers--125 to 500 mg every twelve hours. Gonorrhea
is treated with a single, oral 1-gram dose.
-
Children up to 12 years of age who can swallow tablets whole--125
or 250 mg every twelve hours for ten days.
-
For injection
dosage form:
-
Adults and teenagers--750 mg to 3 grams every six to eight hours,
injected into a muscle or vein. Gonorrhea is treated with a single dose of
1.5 grams, injected into a muscle; the total 1.5-gram dose is divided into
two doses and injected into muscles at two separate places on the body, and
given along with a single, oral 1-gram dose of probenecid.
-
Infants and children 1 month of age and older--12.5 to 80 mg
per kg (5.68 to 36.36 mg per pound) of body weight every six to eight hours,
injected into a muscle or vein.
-
Newborns--10 to 50 mg per kg (4.54 to 22.72 mg per pound) of
body weight every eight to twelve hours, injected into a vein.
For cephalexin
-
For bacterial infections:
-
For oral
dosage forms (capsules, oral
suspension, or tablets):
-
Adults and teenagers--250 milligrams (mg) to 1 gram every six
to twelve hours.
-
Children 40 kg (88 pounds) of body weight and over--250 mg to
1 gram every six to twelve hours.
-
Children 1 year of age and older and up to 40 kg (88 pounds) of body
weight--6.25 to 25 mg per kilogram (kg) (2.84 to 11.36 mg per pound)
of body weight every six hours, or 12.5 to 50 mg per kg (5.68 to 22.72 mg
per pound) of body weight every twelve hours.
-
Infants and children 1 month to 1 year of age--6.25 to 12.5
mg per kg (2.84 to 5.68 mg per pound) of body weight every six hours.
For cephalothin
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams (mg) to 2 grams every four
to six hours, injected into a muscle or vein.
-
Children--13.3 to 26.6 mg per kilogram (kg) (6.04 to 12.09 mg
per pound) of body weight every four hours, or 20 to 40 mg per kg (9.09 to
18.18 mg per pound) of body weight every six hours, injected into a muscle
or vein.
For cephapirin
-
For bacterial infections:
-
For injection
dosage form:
-
Adults and teenagers--500 milligrams (mg) to 1 gram every four
to six hours, injected into a muscle or vein.
-
Infants and children 3 months of age and older--10 to 20 mg
per kilogram (kg) (4.54 to 9.09 mg per pound) of body weight every six hours,
injected into a muscle or vein.
For cephradine
-
For bacterial infections:
-
For oral
dosage forms (capsules or oral
suspension):
-
Adults and teenagers--250 milligrams (mg) to 1 gram every six
to twelve hours.
-
Infants and children 9 months of age and older--6.25 mg to 1
gram per kilogram (kg) (2.84 to 454 mg per pound) of body weight every six
hours, or 12.5 to 50 mg per kg (5.68 to 22.72 mg per pound) of body weight
every twelve hours.
Missed dose--If you miss a dose of this medicine, take it as
soon as possible. This will help to keep a constant amount of medicine in
the blood or urine. However, if it is almost time for your next dose, skip
the missed dose and go back to your regular dosing schedule. Do not double
doses.
Storage--To store this medicine:
-
Keep out of the reach of children.
-
Store away from heat and direct light.
-
Do not store the capsule or tablet form of this medicine in the bathroom,
near the kitchen sink, or in other damp places. Heat or moisture may cause
the medicine to break down.
-
Store the oral liquid form of most cephalosporins in the refrigerator
because heat will cause this medicine to break down. However, keep the medicine
from freezing. Follow the directions on the label. Cefixime oral suspension
( Suprax
) , cefuroxime axetil oral suspension ( Ceftin
), and cefdinir oral suspension (Omnicef
) do not need to be refrigerated.
-
Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.
Precautions While Using This Medicine
If your
symptoms do not improve within a few days, or if they become worse, check
with your doctor.
For patients with diabetes
:
-
This medicine may cause false test results with
some urine sugar tests
. Check with your doctor before changing your
diet or the dosage of your diabetes medicine.
For patients with phenylketonuria (PKU)
:
-
Cefprozil oral suspension ( Cefzil
) contains
phenylalanine. Check with your doctor before taking this medicine.
In some patients, cephalosporins may cause diarrhea:
-
Severe diarrhea may be a sign of a serious side effect. Do not take any diarrhea medicine without first checking with your doctor
. Diarrhea medicines may make your diarrhea worse or make it last longer.
-
For mild diarrhea, diarrhea medicine containing kaolin or attapulgite
(e.g., Kaopectate
tablets, Diasorb
) may be taken. However, other kinds of diarrhea medicine should
not be taken. They may make your diarrhea worse or make it last longer.
-
If you have any questions about this or if mild diarrhea continues
or gets worse, check with your health care professional.
For patients receiving cefamandole, cefoperazone,
or cefotetan by injection
:
-
Drinking alcoholic beverages or taking other alcohol-containing preparations
(for example, elixirs, cough syrups, tonics, or injections of alcohol) while
receiving these medicines may cause problems. The problems may occur if you
consume alcohol even several days after you stop taking the cephalosporin.
Drinking alcoholic beverages may result in increased side effects such as
abdominal or stomach cramps, nausea, vomiting, headache, fainting, fast or
irregular heartbeat, difficult breathing, sweating, or redness of the face
or skin. These effects usually start within 15 to 30 minutes after you drink
alcohol and may not go away for up to several hours. Therefore, you should not drink alcoholic beverages or take other alcohol-containing
preparations while you are receiving these medicines and for several days
after stopping them
.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects.
Although not all of these side effects may occur, if they do occur they may
need medical attention.
Check with your doctor immediately
if any of
the following side effects occur:
Less common or rare
Abdominal or stomach cramps and pain (severe); abdominal tenderness; diarrhea (watery and severe,
which may also be bloody); fever; unusual bleeding or bruising (more common for cefamandole, cefoperazone, and
cefotetan)
Note: |
Some of these side effects also may occur up to several weeks after
you stop taking this medicine. |
Rare
Blistering, peeling, or loosening of skin; convulsions (seizures); decrease in urine output; hearing loss (more common with cefuroxime treatment
for meningitis; joint pain; loss of appetite, nausea, or vomiting (more common with ceftriaxone); pain, redness, and swelling at place of injection; skin rash, itching, redness, or swelling; trouble in breathing; unusual tiredness or weakness; yellowing of the eyes or skin
Other side effects may occur
that usually do not need medical attention. These side effects may go away
during treatment as your body adjusts to the medicine. However, check with
your doctor if any of the following side effects continue or are bothersome:
More common (less common with some cephalosporins)
Diarrhea (mild); headache; sore mouth or tongue; stomach cramps
(mild); vaginal itching or discharge
Other side effects not listed above
may also occur in some patients. If you notice any other effects, check with
your doctor.
Additional Information
Once a medicine has been approved for marketing
for a certain use, experience may show that it is also useful for other medical
problems. Although these uses are not included in product labeling, cephalosporins
are used in certain patients with the following medical conditions:
-
Amoxicillin-resistant sinusitis (treatment)--Cefaclor
-
Bacterial endocarditis (Prophylaxis)--Cefadroxil, cefazolin,
and cephalexin
-
Melioidosis (treatment)--Ceftazidime
Other than the above information, there is no additional information relating
to proper use, precautions, or side effects for these uses.