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Some commonly used brand names are:
In the U.S.--
In Canada--
Droperidol (droe-PER-i-dole) is used to produce sleepiness or drowsiness before surgery or certain procedures. It is also used to prevent nausea and vomiting after surgery.
This medicine is available only with your doctor's prescription, in the following dosage form(s):
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For droperidol, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to droperidol, haloperidol, or similar medicines. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy--Droperidol has been used in some pregnant patients. There was no increase in premature births or birth defects when droperidol was used. Droperidol has been used in patients undergoing cesarean section. Newborn babies whose mothers received droperidol did not have an increase in breathing problems.
Breast-feeding--Droperidol passes into breast milk. Breast-feeding is not recommended while you are receiving droperidol.
Children--Droperidol has not been studied in children up to 2 years of age. There is no specific information comparing the use of droperidol in children with use in other age groups. However, based on experience with similar drugs, children may be more likely than older patients to experience side effects after receiving droperidol, such as muscle spasms in the tongue, face, neck, and back, and inability to move the eyes.
Older adults--Older patients may be more likely than younger adult patients to experience dizziness and excessive sleepiness from droperidol.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other drugs, including nonprescription (over-the-counter [OTC]) medicine.
Other medical problems--The presence of other medical problems may affect the use of droperidol. Make sure you tell your doctor if you have any other medical problems, especially:
Dosing--The dose of droperidol will be different for different patients. Your health care professional will decide on the right amount for you, depending on:
For patients going home within a few hours after surgery:
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Less common
Anxiety; high blood pressure; restlessness
Rare
Fever; fixed upward position of the eyeballs; spasm of the muscles of the tongue, face, neck, and back
Side effects are possible for one or two days after you receive droperidol. During this period of time, check with your doctor if you notice any of the side effects listed above.
Symptoms of overdose
Dizziness; fixed upward position of the eyeballs; restlessness; slowed breathing; spasm of the muscles of the tongue, face, neck, and back
Other side effects may occur that usually do not need medical attention. However, check with your doctor if any of the following side effects continue or are bothersome:
More common
Drowsiness; lightheadedness; rapid heart rate
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, droperidol is used in certain patients with the following medical condition:
For patients receiving this medicine for severe agitation and combativeness, the dose administered will depend on the degree of agitation and the size of the patient.
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