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Some commonly used brand names are:
In the U.S.--
In Canada--
Generic name product may be available in the U.S. and Canada.
Other commonly used names are nicotinic acid or vitamin B 3 .
Niacin (NYE-a-sin) is used to help lower high cholesterol and fat levels in the blood. This may help prevent medical problems caused by cholesterol and fat clogging the blood vessels.
Some strengths of niacin are available only with your doctor's prescription. Others are available without a prescription, since niacin is also a vitamin. However, it is best to take it only under your doctor's direction so that you can be sure you are taking the correct dose.
Niacin for use in the treatment of high cholesterol is available in the following dosage forms:
If you are taking this medicine without a prescription, carefully read and follow any precautions on the label. For niacin, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to niacin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Diet--Before prescribing medicine for your condition, your doctor will probably try to control your condition by prescribing a personal diet for you. Such a diet may be low in fats, sugars, and/or cholesterol. Many people are able to control their condition by carefully following their doctor's orders for proper diet and exercise. Medicine is prescribed only when additional help is needed and is effective only when a schedule of diet and exercise is properly followed.
Also, this medicine is less effective if you are greatly overweight. It may be very important for you to go on a reducing diet. However, check with your doctor before going on any diet.
Make certain your health care professional knows if you are on any special diet, such as a low-sodium or low-sugar diet.
Pregnancy--Studies have not been done in either humans or animals.
Breast-feeding--Niacin has not been reported to cause problems in nursing babies.
Children--There is no specific information comparing the use of niacin for high cholesterol in children with use in other age groups. However, use is not recommended in children under 2 years of age since cholesterol is needed for normal development.
Older adults--Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Although there is no specific information comparing the use of niacin for high cholesterol in the elderly with use in other age groups, it is not expected to cause different side effects or problems in older people than in younger adults.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other medical problems--The presence of other medical problems may affect the use of niacin. Make sure you tell your doctor if you have any other medical problems, especially:
Use this medicine only as directed by your doctor . Do not use more or less of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.
Remember that niacin will not cure your condition but it does help control it. Therefore, you must continue to take it as directed if you expect to keep your cholesterol levels down.
Follow carefully the special diet your doctor gave you . This is the most important part of controlling your condition, and is necessary if the medicine is to work properly.
If this medicine upsets your stomach, it may be taken with meals or milk. If stomach upset (nausea or diarrhea) continues, check with your doctor.
For patients taking the extended-release capsule form of this medicine:
For patients taking the extended-release tablet form of this medicine:
Dosing--The dose of niacin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of niacin. If your dose is different, do not change it unless your doctor tells you to do so.
The number of capsules or tablets or teaspoonfuls of solution that you take depends on the strength of the medicine.
Missed dose--If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage--To store this medicine:
It is very important that your doctor check your progress at regular visits . This will allow your doctor to see if the medicine is working properly to lower your cholesterol and triglyceride (fat) levels and if you should continue to take it.
Do not stop taking niacin without first checking with your doctor . When you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may want you to follow a special diet to help prevent this from happening.
This medicine may cause you to feel dizzy or faint, especially when you get up from a lying or sitting position. Getting up slowly may help. This effect should lessen after a week or two as your body gets used to the medicine. However, if the problem continues or gets worse, check with your doctor.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
Less common
With prolonged use of extended-release niacin
Darkening of urine; light gray-colored stools; loss of appetite; severe stomach pain; yellow eyes or skin
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Less common
Feeling of warmth; flushing or redness of skin, especially on face and neck; headache
With high doses
Diarrhea; dizziness or faintness; dryness of skin; fever; frequent urination; itching of skin; joint pain; muscle aching or cramping; nausea or vomiting; side, lower back, or stomach pain; swelling of feet or lower legs; unusual thirst; unusual tiredness or weakness; unusually fast, slow, or irregular heartbeat
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your health care professional.
Revised: 11/09/91
Interim revision: 08/10/94
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