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| Other drug names: | A-Am An-Az B C-Ch Ci-Cz D-Dh Di-Dz E F G H I-J K-L M-Mh Mi-Mz N-Nh Ni-Nz O P-Pl Pm-Pz Q-R S-Sn So-Sz T-To Tp-Tz U-V W-Z 0-9 |
| Contents of this page: | |
Some commonly used brand names are:
In the U.S.--
In Canada--
Pentamidine (pen-TAM-i-deen) is used to try to prevent Pneumocystis carinii (noo-moe-SISS-tis) pneumonia (PCP), a very serious type of pneumonia. This type of pneumonia occurs commonly in patients whose immune systems are not working normally, such as patients with acquired immune deficiency syndrome (AIDS). Inhaled pentamidine does not prevent illness in parts of the body outside the lungs. This medicine may also be used for other conditions as determined by your doctor.
Pentamidine is available only with your doctor's prescription, in the following dosage form:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pentamidine inhalation, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to pentamidine inhalation. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy--Studies on birth defects have not been done in humans. However, studies in rabbits, given doses by injection much larger than humans would absorb into their bloodstream through the lungs, have shown an increase in miscarriages and bone defects in the fetus.
Breast-feeding--It is not known whether pentamidine passes into breast milk. However, pentamidine has not been reported to cause problems in nursing babies.
Children--Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of pentamidine inhalation in children with use in other age groups. However, pentamidine inhalation is recommended in children 5 years of age and older who cannot tolerate other medicines.
Older adults--Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of pentamidine inhalation in the elderly with use in other age groups.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other medical problems--The presence of other medical problems may affect the use of pentamidine inhalation. Make sure you tell your doctor if you have any other medical problems, especially:
To help prevent the development or return of pneumocystis pneumonia, you must receive pentamidine inhalation on a regular basis, even if you are feeling well.
Dosing--The dose of pentamidine inhalation will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of pentamidine inhalation. If your dose is different, do not change it unless your doctor tells you to do so.
Missed dose--If you miss a dose of this medicine, receive your
treatment as soon as possible. If you are also using the
inhalation form of a bronchodilator (medicine used to help relieve breathing
problems), use the pentamidine inhalation at least 5 to 10 minutes after the
bronchodilator, unless otherwise directed by your doctor. This will help to
reduce the possibility of side effects. Do not use the bronchodilator or any
medicine other than pentamidine in the nebulizer. A bitter or metallic taste may occur during use of this medicine. Sucking
on a hard candy after each treatment can help reduce this problem. Cigarette smoking can increase the chance of coughing and difficulty in
breathing during pentamidine inhalation therapy. On rare occasions, pneumocystis infections have occurred in parts of the
body outside the lungs in patients receiving pentamidine inhalation therapy.
You should discuss this possible problem with your doctor. Along with its needed effects, a medicine may cause some unwanted effects.
Although not all of these side effects may occur, if they do occur they may
need medical attention. Check with your health care professional immediately
if any of the following side effects occur: More common Burning pain, dryness, or sensation of lump in throat; chest pain or congestion; coughing; difficulty in breathing; difficulty
in swallowing; skin rash; wheezing Rare Nausea and vomiting; pain in upper abdomen,
possibly radiating to the back; pain in side of chest
(severe); shortness of breath (sudden and severe) Rare--with daily treatment doses only Anxiety; chills; cold sweats; cool, pale skin; decreased
urination; headache; increased
hunger; loss of appetite; nausea and vomiting; nervousness; shakiness; stomach pain; unusual tiredness Other
side effects not listed above may also occur in some patients. If you notice
any other effects, check with your doctor.
Revised: 03/03/92
Precautions While Using This Medicine
Side Effects of This Medicine
Interim revision: 03/28/94
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