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Some commonly used brand names are:
In the U.S.--
In Canada--
Risperidone (ris-PER-i-done) is used to treat the symptoms of psychotic disorders, such as schizophrenia.
Risperidone is available only with your doctor's prescription, in the following dosage forms:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For risperidone, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to risperidone. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy--Studies with risperidone have not been done in pregnant women. One baby whose mother took risperidone during pregnancy was born with a serious brain problem. However, it is not known whether this problem was caused by risperidone. Some unwanted effects have been reported in animal studies, but the risk to human babies is not clear. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding--Risperidone has been shown to pass into the milk of nursing animals. It may also pass into human milk and may cause unwanted effects, such as behavior changes, in nursing babies. It may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.
Children--Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of risperidone in children with use in other age groups.
Older adults--Elderly people may be especially sensitive to the effects of risperidone. This may increase the chance of having side effects during treatment.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking risperidone, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems--The presence of other medical problems may affect the use of risperidone. Make sure you tell your doctor if you have any other medical problems, especially:
Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more or less of it, do not take it more or less often, and do not take it for a longer or shorter time than your doctor ordered.
Dosing--The dose of risperidone will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of risperidone. If your dose is different, do not change it unless your doctor tells you to do so.
For patients taking the oral solution form of risperidone:
Missed dose--If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage--To store this medicine:
Your doctor should check your progress at regular visits , especially during the first few months of treatment with this medicine. This will allow the dosage to be changed if necessary to meet your needs.
Do not stop taking this medicine without first checking with your doctor . Your doctor may want you to reduce gradually the amount you are taking before stopping completely. This is to prevent side effects and to keep your condition from becoming worse.
This medicine may add to the effects of alcohol and other CNS depressants (medicine that makes you drowsy or less alert) . Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine .
Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine . Taking risperidone together with medicines that are used during surgery, dental, or emergency treatments may increase the CNS depressant effects.
This medicine may cause blurred vision, dizziness, or drowsiness. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see clearly .
Dizziness, lightheadedness, or fainting may occur , especially when you get up from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor.
Risperidone may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:
If you have a severe reaction from the sun, check with your doctor .
This medicine may make it more difficult for your body to keep a constant temperature. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heatstroke. Hot baths or saunas may make you feel dizzy or faint while you are taking this medicine. Also, use extra care not to become too cold while you are taking risperidone. If you become too cold, you may feel drowsy, confused, or clumsy.
Along with its needed effects, risperidone can sometimes cause serious side effects. Tardive dyskinesia (a movement disorder) may occur and may not go away after you stop using the medicine. Signs of tardive dyskinesia include fine, worm-like movements of the tongue, or other uncontrolled movements of the mouth, tongue, cheeks, jaw, or arms and legs. Other serious but rare side effects may also occur. These include neuroleptic malignant syndrome (NMS), which may cause severe muscle stiffness, fever, severe tiredness or weakness, fast heartbeat, difficult breathing, increased sweating, loss of bladder control, or seizures. You and your doctor should discuss the good this medicine will do as well as the risks of taking it .
Stop taking risperidone and get emergency help immediately if any of the following side effects occur:
Rare
Convulsions (seizures); difficult or fast breathing; fast heartbeat or irregular pulse; fever (high); high or low blood pressure; increased sweating; loss of bladder control; muscle stiffness (severe); unusually pale skin; unusual tiredness or weakness (severe)
Check with your doctor immediately if any of the following side effects occur:
More common
Difficulty in speaking or swallowing; inability to move eyes; muscle spasms of face, neck, and back; twisting movements of body
Rare
High body temperature (dizziness; fast, shallow breathing; fast, weak heartbeat; headache; muscle cramps; pale, clammy skin; increased thirst); lip smacking or puckering; low body temperature (confusion, drowsiness, poor coordination, shivering); prolonged, painful, inappropriate erection of the penis; puffing of cheeks; rapid or worm-like movements of tongue; uncontrolled chewing movements; uncontrolled movements of arms and legs
Check with your doctor as soon as possible if any of the following side effects occur:
More common
Anxiety or nervousness; changes in vision, including blurred vision; decreased sexual desire or performance; loss of balance control; mask-like face; menstrual changes; mood or mental changes, including aggressive behavior, agitation, difficulty in concentration, and memory problems; problems in urination or increase in amount of urine; restlessness or need to keep moving (severe); shuffling walk; skin rash or itching; stiffness or weakness of arms or legs; tic-like or twitching movements; trembling and shaking of fingers and hands; trouble in sleeping
Less common
Back pain; chest pain; seborrhea (skin condition that may include dandruff and oily skin); unusual secretion of milk
Rare
Extreme thirst; increased blinking or spasms of eyelid; loss of appetite; talking, feeling, and acting with excitement and activity that cannot be controlled; uncontrolled twisting movements of neck, trunk, arms, or legs; unusual bleeding or bruising; unusual facial expressions or body positions
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
More common
Constipation; coughing; diarrhea; drowsiness; dryness of mouth; headache; heartburn; increased dream activity; increased length of sleep; nausea; sore throat; stuffy or runny nose; unusual tiredness or weakness; weight gain
Less common
Darkening of skin color; dry skin; increased sensitivity of the skin to sun; increased watering of mouth; joint pain; stomach pain; vomiting; weight loss
Some side effects, such as uncontrolled movements of the mouth, tongue, and jaw, or uncontrolled movements of arms and legs, may occur after you have stopped taking this medicine. If you notice any of these effects, check with your doctor as soon as possible.
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Developed: 08/15/95
Revised: 08/07/98
Interim revision:
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