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| Other drug names: | A-Am An-Az B C-Ch Ci-Cz D-Dh Di-Dz E F G H I-J K-L M-Mh Mi-Mz N-Nh Ni-Nz O P-Pl Pm-Pz Q-R S-Sn So-Sz T-To Tp-Tz U-V W-Z 0-9 |
| Contents of this page: | |
Some commonly used brand names are:
In the U.S.--
TNKTNK-tPATNK-tissue plasminogen activator
Tenecteplase ((TEN-neck-te-place)) is used to dissolve blood clots that have formed in the blood vessels of the heart and seriously lessen the flow of blood in the heart. This medicine is used to improve survival after a heart attack.
Tenecteplase is to be administered only by or under the immediate supervision of your doctor, it is available in the following dosage forms:
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tenecteplase, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to tenecteplase. Also tell your doctor and pharmacist if you are allergic to any other substances.
Pregnancy--Tenecteplase has not been studied in pregnant women. However, studies in rabbits have shown that multiple intravenous administrations of tenecteplase cause maternal and embryo toxicity, but no fetal abnormalities have been observed. Tenecteplase does not cause maternal and embryo toxicity in rabbits after a single intravenous administration. Before taking this medicine, make sure your doctor knows if you are pregnant or if you have recently had a baby.
The most common adverse effect of tenecteplase therapy is bleeding, and pregnancy can increase this risk.
Breast-feeding-- It is not known whether tenecteplase passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who have been given this medicine and who wish to breast-feed should discuss this with their doctor.
Children--Children--Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of tenecteplase in children with use in other age groups.
Older adults--The need for treatment with tenecteplase may be increased in elderly patients with blood clots. However, the chance of bleeding may also be increased. It is especially important that you discuss the use of this medicine with your doctor.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Before you receive tenecteplase, it is especially important that your doctor know if you are taking any of the following:
Other medical problems--Other medical problems or recent childbirth. The presence of other medical problems or recent delivery of a child may affect the use of tenecteplase. Make sure you tell your doctor if you have any other medical problems, especially:
Also, tell your doctor if you have recently had any of the following conditions:
If you have recently had a baby, use of this medicine may cause serious bleeding.
Dosing--The dose of tenecteplase will be different for different patients.
The dose you receive will depend on your body weight. Tenecteplase
can cause bleeding that usually is not serious. However, serious bleeding
may occur in some people. To help prevent serious bleeding,
carefully follow any instructions given by your health care professional.
Also, move around and be handled as little as possible, and do not get out
of bed on your own, unless your health care professional tells you it is all
right to do so
. Do not take other medicines unless they have been discussed with your doctor.
This especially includes nonprescription medicines, such as aspirin. Along with its needed effects, a medicine
may cause some unwanted effects. Although not all of these side effects may
occur, if they do occur they may need medical attention. Check with your doctor
immediately
if any of the following side effects occur: More common Bleeding or bruising of any kind, especially
around the place of injection; collection of blood
under skin
Less common or rare Abdominal or stomach pain or swelling; back pain or backaches; blood in throat; blood in urine; bloody or black, tarry
stools; constipation; cough; coughing up blood; difficulty
swallowing; dizziness; fast, slow or irregular breathing; fast, slow or
irregular heartbeat; headaches; hives; nosebleeds; shortness
of breath and/or wheezing; skin rash, hives or itching; swelling of eyes, face, lips, or tongue; tightness in chest; unusual tiredness
or weakness; vomiting of blood or material that looks
like coffee grounds; wheezing Other side effects may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts to the
medicine. However, check with your doctor if any of the following side effects
continue or are bothersome. Less common Bloody nose; unexplained nosebleeds
Precautions While Using This Medicine
Side Effects of This Medicine
Developed: 07/28/2000
Revised:
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