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Some commonly used brand names are:
In the U.S.--
In Canada--
Tinzaparin (tin-ZA-pa-rin) is used for the prevention and/or treatment of deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Tinzaparin is used for several days after surgery, while you are unable to walk. It is during this time that blood clots are most likely to form. Tinzaparin also may be used for other conditions as determined by your doctor.
This medicine is available only with your doctor's prescription, in the following dosage forms:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tinzaparin, the following should be considered:
Allergies--Tell your doctor if you have ever had any unusual or allergic reaction to tinzaparin. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, especially pork or pork products, preservatives, or dyes.
Pregnancy--Tinzaparin has not been studied in pregnant women. However, tinzaparin has not been shown to cause birth defects or other problems in animal studies.
Breast-feeding-- It is not known whether tinzaparin passes into breast milk. Breast-feeding is not recommended while taking this medicine. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.
Children--Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of tinzaparin in children with use in other age groups.
Older adults--This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.
Other medicines--Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are using tinzaparin, it is especially important that your doctor and pharmacist know if you are taking any of the following:
Other medical problems--The presence of other medical problems may affect the use of tinzaparin. Make sure you tell your doctor if you have any other medical problems, especially:
If you are using tinzaparin at home, your health care professional will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your health care professional if you have any problems using the medicine .
Put used syringes in a puncture-resistant, disposable container , or dispose of them as directed by your health care professional.
Dosing--The dose of tinzaparin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of tinzaparin. If your dose is different, do not change it unless your doctor tells you to do so.
Missed dose--If you miss a dose of this medicine, discuss this with your physician.
Storage--To store this medicine:
Tell all your medical doctors and dentists that you are using this medicine .
Check with your doctor immediately if you notice any of the following side effects:
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Deep, dark purple bruise, pain, or swelling at place of injection
Less common
Bladder pain; bleeding gums; blood in urine; bloody or cloudy urine; blurred vision; chest pain; chest tightness; chills; confusion; cough; coughing up blood; difficulty in breathing or swallowing; dizziness; faintness, or lightheadedness when getting up from a lying or sitting position suddenly; fast, slow, or irregular heartbeat; fever; frequent urge to urinate; headache; increased menstrual flow or vaginal bleeding; lower back pain or side pain; nosebleeds; pain or burning while urinating; painful or difficult urination; pale skin; palpitations; paralysis; pounding in the ears; prolonged bleeding from cuts; red or dark brown urine; red or black, tarry stools; severe or continuing dull nervousness; shortness of breath; skin rash; sore throat; sores, ulcers, or white spots on lips or in mouth; sweating; swollen glands; troubled breathing, exertional; unexplained pain, swelling, or discomfort, especially in the chest, abdomen, joints, or muscles; unusual bleeding or bruising; unusual tiredness or weakness; vomiting of blood or coffee ground-like material
Rare
Blue-green to black skin discoloration; bowel/bladder dysfunction; hives; itching; leg weakness; numbness; pain, redness, or sloughing of skin at place of injection; paresthesia; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; wheezing
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.
Less common or Rare
Constipation; nausea and vomiting; prolonged, painful, inappropriate erection of the penis; trouble in sleeping
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
Developed: 08/11/2000
Revised:
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