Ectopic Cushing's syndrome

Alternative names:

Cushing's syndrome - ectopic

Treatment:

Cushing's syndrome that is due to an ectopic ACTH secreting tumor are resected (surgically removed), if possible. In benign tumors such as thymomas, or pheochromocytoma, this is usually possible. However, many tumors are malignant (growing worse and resisting treatment) and have metastasized (spread to other areas) before cortisol excess has been diagnosed and resection is not possible. Drugs to suppress cortisol secretion may be given in such situations. The drugs include ketoconazole, aminoglutethimide, or metyrapone.

Expectations (prognosis):

Tumor resection may lead to full recovery, but there is a chance of tumor recurrence. Survival for people with ectopic tumors depends upon the outcome associated with the particular tumor type.

Complications:

• metastasis of tumor
• continue cortisol excess

Calling your health care provider:

Call your health care provider if symptoms of Cushing's syndrome appear.