Cushing's syndrome
Alternative names:
hypercortisolism
Treatment:
Treatment depends upon the cause of the disorder. In Cushing's syndrome caused by drug therapy with corticosteroids, the drug must be slowly decreased under medical supervision.
In Cushing's disease caused by a pituitary tumor, surgery to remove the tumor is recommended. Hydrocortisone replacement therapy is needed until the pituitary returns to normal function.
Cushing's syndrome caused by an adrenal tumor is usually treated by surgical removal of the tumor. In inoperable cases, certain medications can suppress the secretion of cortisol.
In Cushing's syndrome caused by an ectopic ACTH-secreting tumor, the tumor is resected.
Cortisol replacement therapy is indicated after surgery until cortisol production resumes. In some cases, life-long therapy with cortisone drugs becomes necessary.
Expectations (prognosis):
Tumor removal may lead to full recovery, but there is a chance of recurrence. Survival for people with ectopic tumors depends upon the probable outcome associated with the particular tumor type. Untreated, Cushing's syndrome can lead to death.
Complications:
Calling your health care provider:
Call your health care provider if symptoms develop that indicate Cushing's syndrome.
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