MEDLINEplus Health Information: Return to home page   A service of the National Library of Medicine: Go to NLM home page
Search     Advanced Search    Site Map    About MEDLINEplus    Home
Health Topics: conditions, diseases and wellness Drug Information: generic and brand name drugs Dictionaries: spellings and definitions of medical terms Directories: doctors, dentists and hospitals Other Resources: organizations, libraries, publications, MEDLINE

Medical Encyclopedia

Disease     Injury     Nutrition     Poison     Special     Surgery     Symptoms     Tests

 
Overview   Symptoms   Treatment   Prevention   

Necrotizing vasculitis

Alternative names:

vasculitis - necrotizing

Definition:

An inflammatory condition of blood vessels characterized by tissue death, scarring, and proliferation of the walls of the blood vessels, which may result in blockage of the vessel.

Causes, incidence, and risk factors:

Necrotizing vasculitis is uncommon, occurring in 6 out of 10,000 people. It may occur in rheumatoid arthritis and is commonly seen with systemic lupus erythematosus, periarteritis nodosa, and progressive systemic sclerosis. It is very rare in children.

The disorder involves inflammation of the lining of the blood vessels. The cause of the inflammation is unknown, but is likely related to autoimmune factors. The tissues become necrotic (dead). The wall of the vessel may scar and thicken. The vessel may close off (occlude), causing lack of blood flow to the tissues supplied by that blood vessel with subsequent infarction (tissue death) of the tissues.

Necrotizing vasculitis may affect any blood vessel of the body, and therefore any part of the body, including the muscles, nerves, kidneys, liver, or any other area.


Adam

The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2000 adam.com, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

Health Topics | Drug Information | Dictionaries | Directories | Other Resources