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Primary myelofibrosis

Alternative names:

agnogenic myeloid metaplasia; idiopathic myelofibrosis; myelofibrosis; myeloid metaplasia

Treatment:

There is no specific treatment for primary myelofibrosis. Blood transfusions are given to correct anemia. Recombinant erythropoietin or androgens may stimulate red blood cell production and may be beneficial. Splenectomy (removal of the spleen) may be indicated where splenic enlargement causes symptoms related to its size. Radiation and chemotherapy may also be used.

Expectations (prognosis):

The median survival of people with primary myelofibrosis is about 5 years. However, many people survive for decades. End-stage disease is a wasting illness with debility.

Complications:

Calling your health care provider:

Call for an appointment with your health care provider if symptoms of this disorder develop. Uncontrolled bleeding, shortness of breath, jaundice, and progressive confusion are symptoms that indicate a need for urgent or emergency care.


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