Chronic myelogenous leukemia (CML)

Alternative names:

chronic granulocytic leukemia; chronic myelocytic leukemia

Treatment:

Treatment is aimed at suppressing the bone marrow and may induce a remission with good control of the signs and symptoms of the disease.

The chronic phase can be controlled with chemotherapy, which can be given as an outpatient treatment. Interferon therapy has recently been used to achieve temporary remission.

A bone marrow transplant preceded by high dose chemotherapy and radiation therapy has led to long-term disease-free survival in some people. However, not all people are suitable candidates for transplantation, or have a suitable donor.

SELF CARE MEASURES
To minimize bleeding, apply ice and pressure to any external bleeding. A soft toothbrush and electric razor should be used for personal hygiene. An increase in calories and protein in diet may help reduce the side effects associated with chemotherapy. Planning daily activities with scheduled rest periods can help to prevent the fatigue associated with anemia.

Support groups:

The stress of illness can often be helped by joining a support group where members share common experiences and problems. For this condition, see cancer - support group and leukemia - support group.

Expectations (prognosis):

Without curative treatment, the disease is fatal. Median survival is 3 to 4 years. About 50% of those who receive a bone marrow transplant have long-term disease-free survival.

Complications:

• blast crisis chronic myelogenous leukemia

Calling your health care provider:

Call your health care provider if you have CML and develop a fever over 100 degrees Fahrenheit, chills, sore throat, or cough.