Guillain-Barre
Alternative names:
acute idiopathic polyneuritis; acute inflammatory polyneuropathy; infectious polyneuritis; Landry-Guillain-Barre syndrome
Treatment:
The disease usually subsides spontaneously over time but symptoms may be severe during the course of the disorder. Hospitalization is usually required, and intensive care with life support (support of breathing, especially) may be necessary.
Corticosteroids such as prednisone may reduce inflammation of the nerves. They are not given for acute cases, but may be recommended if the disorder continues to progress. Medications that suppress the immune system may be used for some severe cases.
Plasmapheresis may benefit some cases if used in the initial phase. About 3 weeks, there is usually no benefit. Blood plasma, which contains antibodies, is removed from the body and replaced with intravenous fluids or antibody-free donated plasma.
Other symptoms are treated as necessary. This may include measures to prevent choking during feeding (through positioning or use of a feeding tube), intermittent bladder catheterization, or other treatments.
Expectations (prognosis):
Almost all cases (95%) survive. About 75% recover completely. Mild weakness may persist for some people. However, the disorder may be also be fatal. The outcome is most likely to be very good when symptoms are relieved within 3 weeks after they begin.
Complications:
Calling your health care provider:
Go to the emergency room or call the local emergency number (such as 911) if loss of movement, decreased sensation, or other emergency symptoms occur, including difficulty swallowing or breathing, feeling "unable to take a deep breath", or fainting.
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