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Acanthosis nigricans - close-up
Acanthosis nigricans on the hand
 
Overview   

Acanthosis nigricans

Definition:

A skin condition characterized by increased pigmentation (darkening of the skin) and hyperkeratosis (thickening of the skin). It occurs most commonly in the flexural skin areas (behind knee, front of elbow, neck, etc.). The disorder is related to insulin metabolism and appears in diseases which affect insulin metabolism including obesity. In adults the condition may be associated with malignant tumors.


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