Russell-Silver syndrome
Alternative names:
Russell-Silver dwarfism; Silver syndrome
Definition:
A condition of unknown origin, but which is characterized by extremely short stature and frequent asymmetry.
Causes, incidence, and risk factors:
Genetic problems are thought to play a part in this syndrome although no pattern of inheritance has been determined. Children with Russell-Silver syndrome appear sporadically in families with no prior history of the condition.
Children with Russell-Silver syndrome generally achieve less than 5 feet at adult height. Side-to-side asymmetry is fairly common. This asymmetry may occur anywhere including the face. Other findings include excessive sweating, a small triangular face which makes the skull look large by comparison, inward curved the fingers, and pigmented skin lesions called cafe-au-lait spots.
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