Hyperimmunoglobulin E syndrome

Alternative names:

Job syndrome

Treatment:

There is no known cure for the condition. The goal of treatment is control of the recurrent infections. Medications include antibiotic treatment of infections with whatever antibiotic is specific for the organism causing the infection. Antifungal agents are prescribed when appropriate. Antiviral agents are given when appropriate.

Sometimes surgical drainage of abscesses is needed.

IV gamma globulin may help to build up the immune system temporarily when there are severe infections.

Expectations (prognosis):

Job syndrome is a lifelong chronic condition. Each new infection requires treatment.

Complications:

• repeated infections
• infection spread throughout the body (see sepsis)

Calling your health care provider:

Call your health care provider if you are experiencing or observing a collection of the above signs and symptoms.