Waardenberg syndrome

Alternative names:

Klein-Waardenberg syndrome

Definition:

An inheritable condition, with deafness and partial albinism.

Causes, incidence, and risk factors:

Waardenberg syndrome is inherited as an autosomal dominant trait. The two dominant features are some degree of hearing loss and partial albinism which may appear as a white forelock in an otherwise dark head of hair, very pale light blue eyes, or two different colored eyes (heterochromia). Other findings that may be noted including wide separation of the inner corners of the eyes with a brood nasal bridge and other pigmentary changes of the skin.