Cleidocranial dysostosis

Alternative names:

cleidocranial dysplasia

Symptoms:

• incomplete or absent collar bone
• ability to touch shoulders together in front of body
• loose joints (laxity of joints)
• delayed closure of fontanels (soft spots)
• heavy protruding brow (frontal bossing)
• failure to lose the primary teeth at the expected time
• slow eruption of secondary teeth
• extra teeth (supernumerary teeth)
• peg teeth
• teeth - delayed or absent formation
• low nasal bridge

Signs and tests:

There is often a family history of cleidocranial dysostosis.

Skeletal X-rays show

• undergrowth of the clavicle (collarbone)
• undergrowth of the scapula (shoulder blade)
• failure of the pubic symphysis to close (the bony structures at the front of the pelvis)