Euglobulin lysis time

Alternative names:

euglobulin clot lysis; fibrinolysis/euglobulin lysis

Normal values:

90 minutes to 6 hours
Euglobulin clot lysis is normally complete within 2 to 4 hours.

What abnormal results mean:

In primary fibrinolysis (for example, caused by streptokinase administration, cancer of the prostate, shock), the euglobulin lysis time is shorter than normal.

In DIC, it is usually normal, but if all the plasmin has been consumed, the time may be prolonged.

• Decreased fibrinolysis (increased lysis time) may indicate:
  • diabetes mellitus
  • prematurity

• Increased fibrinolysis (shortened lysis time) may indicate:
  • cirrhosis
  • extensive vascular (blood vessel) trauma or surgery
  • hereditary deficiency of fibrinogen
  • leukemia
  • obstetric complications (for example antepartum hemorrhage, septic - abortion, hydatidiform mole, amniotic embolism)
  • prostatic cancer
  • shock
  • thrombocytopenia purpura

  Additional conditions under which the test may be performed:

  • abortion, spontaneous
  • primary thrombocythemia