Wegener's granulomatosis

Alternative names:

midline granulomatosis

Treatment:

Treatment with corticosteroids, cyclophosphamide, and azathioprine produces long-term remission in approximately 90% of affected people.

Expectations (prognosis):

With treatment, most people recover within a year, although chronic renal failure may develop. Without treatment, the disease is fatal within a few months of diagnosis.

Complications:

• chronic renal failure
• inflammation of the eyes
• nasal septum perforation (hole)
• rash
• side effects of medications used to treat the disease

Note: Complications usually result from lack of treatment.

Calling your health care provider:

Call your health care provider if chest pain, coughing up blood, blood in the urine, or other symptoms of this disorder are present.