Chronic pancreatitis

Alternative names:

chronic relapsing pancreatitis

Definition:

A persistent inflammation of the pancreas, an elongated, tapered gland that is located behind the stomach and secretes digestive enzymes and the hormones insulin and glucagon.

Causes, incidence, and risk factors:

Chronic pancreatitis is caused by alcohol abuse, hemochromatosis (a condition of excess iron in the blood), and other unknown factors. Inflammation and fibrosis cause the destruction of functioning glandular tissue in the pancreas. This results in an inability to properly digest fat caused by a lack of pancreatic enzymes. The production of insulin is also affected. Attacks may become more frequent as the condition progresses. The incidence is 2 out of 10,000 people. Alcoholism is a risk factor. Chronic pancreatitis occurs more frequently in men.