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Autosomal dominant genes
 
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Klinefelter's syndrome

Treatment:

There is no treatment for the infertility associated with this syndrome. Testosterone therapy will improve the development of secondary sexual characteristics. The testicular changes that lead to infertility are not preventable.

Gynecomastia (enlarged breast tissue) can be treated with plastic surgery if it is disfiguring.

Counseling may be of benefit to people with emotional maladjustment due to sexual dysfunction and to reinforce male identity.

Expectations (prognosis):

Infertility cannot be treated. With testosterone therapy, a more normal appearance is the general rule.

Complications:

The syndrome is associated with an increased risk of breast cancer, pulmonary disease, varicose veins, and osteoporosis.

Calling your health care provider:

Call for an appointment with your health care provider if a boy fails to develop secondary sexual characteristics.


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