Systemic lupus erythematosus
Alternative names:
disseminated lupus erythematosus; lupus; lupus erythematosus; SLE
Treatment:
OVERVIEW:
The disease has multiple manifestations with variable severity, which determines individual treatment. There is no cure for SLE.
MEDICATIONS:
Mild disease (rash, headaches, fever, arthritis, pleurisy, pericarditis) requires little therapy. Nonsteroidal anti-inflammatory medications (NSAIDS) are used to treat arthritis and pleurisy. Corticosteroid creams (see Corticosteroids - topical - low potency) are used to treat skin rashes. Antimalarial drugs (hydroxychloroquine) are sometimes used for skin and arthritis symptoms. Sensitivity to light is treated by protective clothing, sunglasses, and sunscreen.
Severe or life-threatening manifestations (hemolytic anemia, extensive heart or lung involvement, kidney disease, central nervous system involvement) often requires treatment by specialists in the specific area. Corticosteroid therapy or medications to suppress the immune system may be prescribed to control the various manifestations of severe disease. Some health care professionals use cytotoxic drugs (drugs that block cell growth) in people who do not have a good response to corticosteroids.
LIFESTYLE CHANGES:
The stress of illness can often be helped by joining a support group where members share common experiences and problems. See lupus - support group.
Expectations (prognosis):
The outcome for people with SLE has improved over recent years. Many of those affected have mild illness. Women with SLE who become pregnant are often able to carry the pregnancy safely to term and deliver normal infants, provided severe renal or heart disease is not present, and the SLE is under treatment. The 10-year survival rate exceeds 85%. People with severe involvement of the brain, lungs, heart, and kidney have the worst prognosis in terms of overall survival and disability.
Complications:
Calling your health care provider:
Call your health care provider if symptoms of SLE are present.
Also call if you have SLE and symptoms worsen, or if new symptoms develop.
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