Reiter's syndrome

Symptoms:

• urinary urgency
• urethral discharge
• burning or stinging on urination
• redness of the eye
• discharge from the eye
• burning eye pain
• joint pain in the large joints (hip pain, knee pain, and ankle pain are common)
• low back pain
• heel pain
• Achilles tendon pain
• small painless ulcers in the mouth, tongue, and glans penis
• skin lesions on the palms and soles that may resemble psoriasis

Additional symptoms that may be associated with this disease:

• urinary hesitancy
• skin redness or inflammation
• penis pain
• incontinence
• genital lesions (male)
• arthritis

Signs and tests:

The diagnosis is based on the clinical features. Since the symptoms may occur at different times, the diagnosis may be delayed. A physical examination may reveal conjunctivitis or typical skin lesions.

Tests that may be performed include:

• joint X-rays
• histocompatibility antigens
• HLA-B27 antigen