Rhabdomyolysis

Symptoms:

• abnormal urine color (dark, red, or cola colored)
• muscle tenderness
• weakness of the affected muscle(s)
• generalized weakness
• muscle stiffness or aching (myalgia)

Additional symptoms that may be associated with this disease:

• weight gain (unintentional)
• seizures
• joint pain
• fatigue

Signs and tests:

An examination reveals tender or damaged skeletal muscles.

• A urinalysis may reveal casts and hemoglobin without formed red blood cells.
• A urine myoglobin test is positive.
• A serum myoglobin test is positive.
• A CPK is very high.
• A serum potassium may be very high (potassium is released from cells into the bloodstream when there is cell breakdown).

This disease may also alter the results of the following tests:

• creatinine - urine
• creatinine
• CPK isoenzymes