Infectious mononucleosis (CMV)

Alternative names:

acute acquired cytomegalovirus infection; mononucleosis - CMV

Symptoms:

• fever
• sore throat
• enlarged lymph nodes, especially in the neck (CMV)
• malaise (vague ill feeling)
• frequent tiredness or fatigue
• loss of appetite
• muscular aches or stiffness
• enlarged spleen
• rash

Less frequently occurring symptoms include:

• jaundice (yellow cast to skin)
• headache
• neck stiffness
• sensitivity to light
• cough
• shortness of breath
• chest pain
• rapid heart rate
• irregular heart rate
• hives

Signs and tests:

A physical examination reveals an enlarged liver and (or) an enlarged spleen. The liver and spleen may be tender when they are gently pressed (palpation). There may be skin rash present.

• A CMV by immunofluorescence may be positive.
• A monospot test may be negative in CMV mononucleosis.
• A CBC shows decreased platelet count and atypical lymphocytes.
• A chemistry panel shows abnormal liver enzyme results.