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Neurofibroma
 
Overview   Symptoms   Treatment   Prevention   

Neurofibromatosis-1

Alternative names:

NF1

Definition:

An inherited disorder characterized by formation of neurofibromas (tumors involving nerve tissue) in the skin, subcutaneous tissue, cranial nerves and spinal root nerves.

Causes, incidence, and risk factors:

NF1 is an autosomal dominant trait, meaning that if either parent has NF1, the offspring have 50 per cent chance of having the disease. NF1 may also appear in a family with no previous history as a new mutation.

Neurofibromatosis causes unchecked growth of neurofibromatous tissue in nerves such as the optic nerve and can cause severe nerve damage leading to loss of function to the area stimulated by that nerve.


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