Skin lesion of Histoplasmosis

Treatment:

The treatment includes treatment for systemic disease and symptomatic relief of the mouth ulcer.

Systemic disease is treated with antifungal medications, intravenously (in a vein) or orally (by mouth). These medications include amphotericin B, ketoconazole, fluconazole, and other potent (and often dangerous) antifungal agents.

Gentle, thorough oral hygiene helps to decrease pain and reduces the risk of infection of the mouth ulcer. Topical antihistamines, antacids, steroids or other medications may be recommended to soothe the area.

Avoid hot or spicy foods, which often increase the mouth pain.

Expectations (prognosis):

The outcome varies. If the underlying infection can be controlled, the skin lesion may disappear. If the infection is not controlled, the disease may progress rapidly and death may occur.

Complications:

• skin lesion usually indicates progressive, chronic, or disseminated Histoplasmosis
• inability to eat or drink because of discomfort from mouth ulcer
• secondary (bacterial) local skin infection
• abscess formation

Calling your health care provider:

Call for an appointment with your health care provider if you think you may have the skin lesion of Histoplasmosis.

Call your health care provider if symptoms worsen or new symptoms occur, including headache, nausea/vomiting, mental status changes, fever, chills, muscle aches or joint aches, stiffness, and cough.

Also call if the skin lesion develops drainage or becomes more painful, reddened, swollen.