Krabbe disease
Alternative names:
globoid cell leukodystrophy
Prevention:
Genetic counseling is recommended for prospective parents with a family history of Krabbe disease. Carrier states may be recognized by decreased galactocerebroside beta-galactosidase levels in their white blood cells or skin fibroblasts. Prenatal diagnosis is possible by measuring galactocerebroside beta-galactosidase levels in cultured amniotic fluid cells or from cultured chorionic villi cells.
|