McCune-Albright syndrome

Alternative names:

Albright syndrome; osteitis fibrosa cystica; polyostotic fibrous dysplasia

Treatment:

There is not a specific treatment for McCune-Albright syndrome. Drugs that inhibit estrogen production, such as testolactone, have been tried with some success. Adrenal abnormalities (such as Cushing syndrome) may be treated by surgery to remove the adrenal glands.

Expectations (prognosis):

Longevity is relatively normal.

Complications:

• repeated episodes of broken bones
• deformity and cosmetic problems resulting from bone abnormalities
• blindness
• deafness

Calling your health care provider:

Call your health care provider if your child develops evidence of premature puberty (before the expected age) or has other symptoms suggestive of McCune-Albright syndrome.