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Overview   Risks   Results   

ACTH (Cortrosyn) stimulation test

Alternative names:

tests of adrenal reserve

What the risks are:

From venipuncture:

  • excessive bleeding
  • fainting or feeling lightheaded
  • hematoma (blood accumulating under the skin)
  • infection (a slight risk any time the skin is broken)
  • multiple punctures to locate veins

Special considerations:

Cortisol amounts vary depending on the time of day. During the first waking hours, the body produces more. The amount decreases the longer a person is awake. If a person normally works nights and sleeps during the day, the test results could be misleading, unless that is taken into account and the time of the test adjusted.


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