Drug-induced hypothyroidism

Definition:

A condition of decreased activity of the thyroid gland that is caused by an adverse reaction to a medication.

Causes, incidence, and risk factors:

Hypothyroidism or underactivity of the thyroid gland may cause a variety of symptoms and may affect all body functions. The body's normal rate of functioning slows causing mental and physical sluggishness. The symptoms may vary from mild to severe. The most severe form of hypothyroidism is called myxedema coma, which is a medical emergency. Severe hypothyroidism, however, is seldom drug related. Drug-induced hypothyroidism is caused by treatment with nitroprusside, lithium, or iodides. The incidence is 2 out of 10,000 people.