Drug-induced hypothyroidism

Treatment:

The drug causing the hypothyroidism must be discontinued, if possible. (DO NOT STOP TAKING PRESCRIBED MEDICATIONS WITHOUT CONSULTING YOUR HEALTH CARE PROVIDER.)

Levothyroxine, a thyroid replacement hormone, is the most commonly used medication, but others are available. The lowest dose effective in relieving symptoms is used. Once the offending drug has been discontinued, the dose can be decreased slowly in increments under medical supervision. After replacement therapy has begun, report symptoms of increased thyroid activity (hyperthyroidism): restlessness, rapid weight loss, sweating.

A high-fiber, low-calorie diet and moderate activity helps relieve constipation and promote weight loss.

Expectations (prognosis):

With early treatment, return to the normal state is usual. However, relapses will occur if the medication is not continued. Myxedema coma can result in death.

Complications:

Myxedema coma, the most severe form of hypothyroidism, is rare. It may be caused by an infection, illness, exposure to cold or certain medications. Symptoms and signs of myxedema coma include unresponsiveness, decreased breathing, low blood pressure, low blood sugar, and below-normal temperature.

Other complications are heart disease, increased risk of infection, infertility, miscarriage in pregnant women, and pituitary tumors (extremely rare).

Calling your health care provider:

Call your health care provider if signs of myxedema are present.

Call your health care provider if chest pain, rapid heart beat, or infection occurs.