Renal tubular acidosis; proximal
Alternative names:
proximal renal tubular acidosis; renal tubular acidosis type II; RTA - proximal; type II RTA
Symptoms:
Signs and tests:
The respiratory rate may be rapid as the body attempts to decrease carbon dioxide in response to decreased bicarbonate levels. Signs and symptoms of osteomalacia or rickets, kidney stones or nephrocalcinosis, or electrolyte disturbances may appear. Signs of dehydration may develop from loss of water into the urine that may accompany excretion of electrolytes.
- The simultaneous measurements of the blood pH and the urine pH may show inadequate hydrogen ion excretion.
- A urinalysis shows abnormalities including excessive levels of phosphate and calcium in the urine. The urine may be alkaline, although this may change as the body becomes more acidic and increasing amounts of bicarbonate are reabsorbed to counteract the acidic condition. A urinalysis may show abnormalities including glucose and amino acids lost as filtration from the kidney becomes abnormal.
- Arterial blood gases and blood chemistries may indicate metabolic acidosis and electrolyte abnormalities.
This disease may also alter the results of the following tests:
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