Acute nonlymphocytic leukemia (AML)

Alternative names:

acute granulocytic leukemia; acute myeloblastic leukemia; acute myelogenous leukemia; myeloid leukemia; splenomedullary leukemia; splenomyelogenous leukemia

Symptoms:

• prolonged bleeding , bruising easily
• gums, bleeding
• epistaxis (bleeding from the nose)
• menstrual periods, abnormal
• skin rash or lesion
  • pinpoint red spots (petechiae)
  • bleeding into the skin
  • bruises (ecchymoses)

• fatigue
• infection - children under 1 year of age are extremely susceptible to streptococcal septicemia.
• fever
• fatigue
• bone pain or tenderness, tenderness of the breastbone (sternum)
• joint pain
  • hip pain
  • knee pain
  • ankle pain
  • foot pain over small joints of the foot
  • shoulder pain
  • elbow pain
  • wrist pain
  • hand - pain over small joints of the hand

• lymphadenopathy (enlarged lymph nodes)
• weight loss
• fever
• gums, swollen
• shortness of breath aggravated by exercise
• paleness
• sensations of feeling the heart beat (palpitations) with an irregular pattern

Signs and tests:

A physical examination shows enlarged liver and spleen.

• A WBC count is abnormal.
• A CBC test shows anemia and low platelet count.
• A bone marrow aspiration shows hypercellularity.
• Low reticulocyte counts - Lymphadenopathy

Children have bone and joint manifestations with areas of bone destruction and periosteal elevation by xray.