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Bullous pemphigoid, close-up of tense blisters
 
Overview   Symptoms   Treatment   Prevention   

Bullous pemphigoid

Symptoms:

  • bullae (large blisters, thin walled sacs filled with clear fluid, greater than 1 cm. diameter)
    • multiple
    • usually located on the arms, legs, or trunk
    • may also occur in the mouth
    • may weep, crust over
    • may appear deep below the surface of the skin
    • may erode the skin, form ulcers or open sores

  • itching
  • rashes
  • mouth sores
  • gums, bleeding

Signs and tests:

Skin lesion biopsy shows subepidermal blister (a blister that occurs beneath the outer skin layer and the inner skin layers) and immunoglobulin deposits.


Adam

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